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IMMUNOGLOBULIN GAMMA-CHAINS
Descriptors Found:
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DeCS
Descriptor
English
:
Immunoglobulin gamma-Chains
Descriptor
Spanish
:
Cadenas gamma de Inmunoglobulina
Descriptor
Portuguese
:
Cadeias gama de Imunoglobulina
Synonyms
English
:
Immunoglobulins, gamma-Chain
Tree Number:
D12.776.124.486.485.114.619.393.522
D12.776.124.486.485.705.500.380
D12.776.124.790.651.114.619.393.522
D12.776.124.790.651.705.500.380
D12.776.377.715.548.114.619.393.522
D12.776.377.715.548.705.500.380
Definition
English
:
Heavy chains of
IMMUNOGLOBULIN G
having a
molecular weight
of approximately 51 kDa. They contain about 450 amino acid residues arranged in four domains and an oligosaccharide component covalently bound to the Fc fragment constant region. The gamma heavy chain subclasses (for example, gamma 1, gamma 2a, and gamma 2b) of the
IMMUNOGLOBULIN G
isotype subclasses (IgG1, IgG2A, and IgG2B) resemble each other more closely than the heavy chains of the other
IMMUNOGLOBULIN ISOTYPES.
Indexing Annotation
English
:
gammopathy: coordinate
IMMUNOGLOBULIN GAMMA-CHAINS
(IM) with
PARAPROTEINEMIAS
(IM) but consider also
HYPERGAMMAGLOBULINEMIA
(IM) or
HEAVY CHAIN DISEASE
(IM), follow text; DF: IG GAMMA CHAIN
Pharmacological Action:
Immunologic Factors
History Note
English
:
2006 (1976)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
CT
contraindications
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
30361
Unique Identifier:
D007142
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS