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LEUKOENCEPHALOPATHY, PROGRESSIVE MULTIFOCAL
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DeCS
Descriptor
English
:
Leukoencephalopathy, Progressive Multifocal
Descriptor
Spanish
:
Leucoencefalopatía Multifocal Progresiva
Descriptor
Portuguese
:
Leucoencefalopatia Multifocal Progressiva
Synonyms
English
:
Encephalitis, JC Polyomavirus
Progressive Multifocal Leukoencephalopathy
Tree Number:
C02.182.525.500
C02.256.721.500
C02.290.575
C02.839.550
C10.228.140.430.520.750.500
C10.228.140.695.750
C10.228.228.245.340.500
C10.228.228.399.750.500
C10.314.450
Definition
English
:
An opportunistic viral
infection
of the
central nervous system
associated with conditions that impair
cell-mediated immunity
(e.g.,
ACQUIRED IMMUNODEFICIENCY SYNDROME
and other
IMMUNOLOGIC DEFICIENCY SYNDROMES
;
HEMATOLOGIC NEOPLASMS
;
IMMUNOSUPPRESSION
; and
COLLAGEN DISEASES
). The causative organism is JC
Polyomavirus
(
JC VIRUS
) which primarily affects oligodendrocytes, resulting in multiple areas of demyelination. Clinical manifestations include
DEMENTIA
;
ATAXIA
; visual disturbances; and other focal neurologic deficits, generally progressing to a vegetative state within 6 months. (From Joynt, Clinical
Neurology
, 1996, Ch26, pp36-7)
History Note
English
:
1973(1971)
Allowable Qualifiers
English
:
BL
blood
CF
cerebrospinal fluid
CI
chemically induced
CL
classification
CO
complications
CN
congenital
DI
diagnosis
DH
diet therapy
DT
drug therapy
EC
economics
EM
embryology
EN
enzymology
EP
epidemiology
EH
ethnology
ET
etiology
GE
genetics
HI
history
IM
immunology
ME
metabolism
MI
microbiology
MO
mortality
NU
nursing
PS
parasitology
PA
pathology
PP
physiopathology
PC
prevention & control
PX
psychology
RA
radiography
RI
radionuclide imaging
RT
radiotherapy
RH
rehabilitation
SU
surgery
TH
therapy
TM
transmission
US
ultrasonography
UR
urine
VE
veterinary
VI
virology
Record Number:
29437
Unique Identifier:
D007968
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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