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PREGNANCY-ASSOCIATED ALPHA 2-GLOBULINS
Descriptors Found:
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DeCS
Descriptor
English
:
Pregnancy-Associated alpha 2-Macroglobulins
Descriptor
Spanish
:
alfa 2-Macroglobulinas Asociadas al Embarazo
Descriptor
Portuguese
:
alfa 2-Macroglobulinas Associadas à Gravidez
Synonyms
English
:
Pregnancy-Associated alpha 2-Globulins
Pregnancy-Associated alpha 2-Glycoproteins
Tree Number:
D12.776.124.790.720.100.500
D12.776.780.675
Definition
English
:
Large (>160 kDa)
glycoproteins
with electrophoretic mobility of
ALPHA-GLOBULINS
, found in high
concentration
in the
plasma
of
pregnant women
but also in a number of species including mouse, rat, and others (
ALPHA-MACROGLOBULINS
). In
humans
, they are always present in the circulation and are nonspecific inhibitors of PROTEINASES,
similar
to
COMPLEMENT PROTEINS
(C3; C4; C5).
History Note
English
:
2004
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
38251
Unique Identifier:
D045384
Occurrence in VHL
:
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