Search on: FLUOROURACIL 
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Descriptor English:   Fluorouracil 
Descriptor Spanish:   Fluorouracilo 
Descriptor Portuguese:   Fluoruracila 
Tree Number:   D03.383.742.698.875.404
Definition English:   A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid. 
Pharmacological Action:   Antimetabolites
Antimetabolites, Antineoplastic
Immunosuppressive Agents
 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   5602 
Unique Identifier:   D005472 

Occurrence in VHL:
 

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