Expresión de búsqueda: GLUTAREDOXINS 
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Descriptor Inglés:   Glutaredoxins 
Descriptor Español:   Glutarredoxinas 
Descriptor Portugués:   Glutarredoxinas 
Sinónimos Inglés:   Glutaredoxin  
Categoría:   D08.811.682.667.084
Definición Inglés:   A family of thioltransferases that contain two active site CYSTEINE residues, which either form a disulfide (oxidized form) or a dithiol (reduced form). They function as an electron carrier in the GLUTHIONE-dependent synthesis of deoxyribonucleotides by RIBONUCLEOTIDE REDUCTASES and may play a role in the deglutathionylation of protein thiols. The oxidized forms of glutaredoxins are directly reduced by the GLUTATHIONE. 
Nota Histórica Inglés:   2008(1980); use PROTEINS 1979 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número del Registro:   52721 
Identificador Único:   D054477 

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