Expresión de búsqueda:
GRANZYMES
Descriptores Encontrados:
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DeCS
Descriptor
Inglés
:
Granzymes
Descriptor
Español
:
Granzimas
Descriptor
Portugués
:
Granzimas
Categoría:
D08.811.277.656.300.760.397
D08.811.277.656.959.350.397
Definición
Inglés
:
A
family
of
serine endopeptidases
found in the SECRETORY GRANULES of
LEUKOCYTES
such as CYTOTOXIC
T-LYMPHOCYTES
and NATURAL KILLER CELLS. When secreted into the
intercellular space
granzymes
act to eliminate transformed and virus-infected host cells.
Acción Farmacológica:
Cytotoxins
Nota Histórica
Inglés
:
2007(1986)
Calificadores Permitidos
Inglés
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número del Registro:
52244
Identificador Único:
D053804
Ocurrencia en la BVS
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS