Expresión de búsqueda:
JANUS KINASES
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DeCS
Descriptor
Inglés
:
Janus Kinases
Descriptor
Español
:
Quinasas Janus
Descriptor
Portugués
:
Janus Quinases
Categoría:
D08.811.913.696.620.682.725.124
D12.776.476.393
Definición
Inglés
:
A
family
of intracellular
tyrosine
kinases that participate in the signaling cascade of
cytokines
by associating with specific
CYTOKINE RECEPTORS
. They act upon
STAT TRANSCRIPTION FACTORS
in signaling pathway referred to as the JAK/STAT pathway. The name Janus kinase refers to the fact the
proteins
have two phosphate-transferring domains.
Nota Histórica
Inglés
:
2007
Calificadores Permitidos
Inglés
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número del Registro:
52252
Identificador Único:
D053612
Ocurrencia en la BVS
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS