Expresión de búsqueda: KARYOPHERINS 
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Descriptor Inglés:   Karyopherins 
Descriptor Español:   Carioferinas 
Descriptor Portugués:   Carioferinas 
Sinónimos Inglés:   Importins  
Categoría:   D12.776.157.530.750.500
D12.776.543.585.750.500
D12.776.660.502
Definición Inglés:   A family of proteins involved in NUCLEOCYTOPLASMIC TRANSPORT. Karyopherins are heteromeric molecules composed two major types of components, ALPHA KARYOPHERINS and BETA KARYOPHERINS, that function together to transport molecules through the NUCLEAR PORE COMPLEX. Several other proteins such as RAN GTP BINDING PROTEIN and CELLULAR APOPTOSIS SUSCEPTIBILITY PROTEIN bind to karyopherins and participate in the transport process. 
Relacionados Inglés:   Active Transport, Cell Nucleus
 
Nota Histórica Inglés:   2002; use KARYOPHERINS (NM) 1995-2001 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   36191 
Identificador Único:   D028884 

Ocurrencia en la BVS:
 

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