Expresión de búsqueda:
LEUKEMIA INHIBITORY FACTOR RECEPTOR ALPHA SUBUNIT
Descriptores Encontrados:
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DeCS
Descriptor
Inglés
:
Leukemia Inhibitory Factor Receptor alpha Subunit
Descriptor
Español
:
Subunidad alfa del Receptor del Factor Inhibidor de Leucemia
Descriptor
Portugués
:
Subunidade alfa de Receptor de Fator Inibidor de Leucemia
Sinónimos
Inglés
:
Antigens, CD118
CD118 Antigens
Categoría:
D12.776.543.750.705.852.583.750
D12.776.543.750.750.400.550.250.750
D23.050.301.264.035.493
D23.101.100.110.493
Definición
Inglés
:
A receptor subunit that combines with
CYTOKINE RECEPTOR GP130
to form the dual specificity receptor for
LEUKEMIA INHIBITORY FACTOR
and
ONCOSTATIN M
. The subunit is also a component of the
CILIARY NEUROTROPHIC FACTOR
RECEPTOR. Both membrane-bound and secreted isoforms of the receptor subunit exist due to
ALTERNATIVE SPLICING
of its mRNA. The secreted isoform is believed to act as an inhibitory receptor, while the membrane-bound form is a signaling receptor.
Nota Histórica
Inglés
:
2007
Calificadores Permitidos
Inglés
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número del Registro:
52379
Identificador Único:
D053680
Ocurrencia en la BVS
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS