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DeCS
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Descriptor Inglés:
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Lissencephaly
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Descriptor Español:
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Lisencefalia
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Descriptor Portugués:
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Lisencefalia
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Sinónimos Inglés:
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Agyria
Pachygyria
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Categoría:
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C10.500.507.450.499
C16.131.666.507.450.499
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Definición Inglés:
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A "smooth brain" malformation of the CEREBRAL CORTEX resulting from abnormal location of developing neurons during corticogenesis. It is characterized by an absence of normal convoluted indentations on the surface of the brain (agyria), or fewer and shallower indentations (pachygryia). There is a reduced number of cortical layers, typically 4 instead of 6, resulting in a thickened cortex, and reduced cerebral white matter that is a reversal of the normal ratio of cerebral white matter to cortex. |
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Nota de Indización Inglés:
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note specifics; MICROLISSENCEPHALY is also available
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Nota Histórica Inglés:
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2008
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Calificadores Permitidos Inglés:
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Número del Registro:
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52594
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Identificador Único:
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D054082
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Ocurrencia en la BVS:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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