Expresión de búsqueda: MATRIX METALLOPROTEINASE 14 
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Descriptor Inglés:   Matrix Metalloproteinase 14 
Descriptor Español:   Metaloproteinasa 14 de la Matriz 
Descriptor Portugués:   Metaloproteinase 14 da Matriz 
Categoría:   D08.811.277.656.300.480.525.300.500
D08.811.277.656.675.374.525.300.500
Definición Inglés:   A transmembrane domain-containing matrix metalloproteinase. It is synthesized as an inactive zymogen that is activated by the action of PROPROTEIN CONVERTASES such as FURIN. Matrix metalloproteinase 14 plays a direct role in the cleavage of proteins in the pericellular environment. In addition, it can function indirectly by enzymatically activating the proprotein form of MATRIX METALLOPROTEINASE 15. 
Combinados Inglés:   Matrix Metalloproteinase 14/antagonists & inhibitors use Matrix Metalloproteinase Inhibitors
 
Nota Histórica Inglés:   2007(1994) 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   52233 
Identificador Único:   D053511 

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