Expresión de búsqueda:
NOD2 SIGNALING ADAPTOR PROTEIN
Descriptores Encontrados:
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DeCS
Descriptor
Inglés
:
Nod2 Signaling Adaptor Protein
Descriptor
Español
:
Proteína Adaptadora de Señalización NOD2
Descriptor
Portugués
:
Proteína Adaptadora de Sinalização NOD2
Sinónimos
Inglés
:
Nucleotide Oligomerization Domain 2 Protein
Categoría:
D12.644.360.024.131.500
D12.644.360.024.307.500
D12.644.360.075.358.500
D12.776.157.057.004.500
D12.776.157.057.068.500
D12.776.476.024.139.500
D12.776.476.024.391.500
D12.776.476.075.358.500
Definición
Inglés
:
A NOD signaling adaptor protein that contains two C-terminal leucine-rich domains which recognize bacterial
PEPTIDOGLYCAN
. It signals via an N-terminal capase recruitment domain that interacts with other
CARD SIGNALING ADAPTOR PROTEINS
such as RIP SERINE-THEONINE KINASES. The protein plays a role in the host defense response by signaling the activation of
CASPASES
and the
MAP KINASE SIGNALING SYSTEM
. Mutations of the gene encoding the
nucleotide oligomerization domain 2 protein
have been associated with increased susceptibility to
CROHN DISEASE.
Nota Histórica
Inglés
:
2007
Calificadores Permitidos
Inglés
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número del Registro:
52307
Identificador Único:
D053473
Ocurrencia en la BVS
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS