Expresión de búsqueda: OSTEOPROTEGERIN 
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Descriptor Inglés:   Osteoprotegerin 
Descriptor Español:   Osteoprotegerina 
Descriptor Portugués:   Osteoprotegerina 
Sinónimos Inglés:   Osteoclastogenesis Inhibitory Factor
Receptors, Tumor Necrosis Factor, Member 11b
Tumor Necrosis Factor Receptor Superfamily, Member 11b  
Categoría:   D12.776.543.750.705.852.760.949.249
Definición Inglés:   A secreted member of the TNF receptor superfamily that negatively regulates osteoclastogenesis. It is a soluble decoy receptor of RANK LIGAND that inhibits both CELL DIFFERENTIATION and function of OSTEOCLASTS by inhibiting the interaction between RANK LIGAND and RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B
Nota Histórica Inglés:   2007(1997) 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   52396 
Identificador Único:   D053244 

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