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RECQ HELICASES
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DeCS
Descriptor
Inglés
:
RecQ Helicases
Descriptor
Español
:
RecQ Helicasas
Descriptor
Portugués
:
RecQ Helicases
Categoría:
D08.811.277.040.025.159.249
D08.811.399.340.249
Definición
Inglés
:
A
family
of structurally-related
DNA helicases
that play an essential role in the
maintenance
of
genome
integrity.
RecQ helicases
were originally discovered in E COLI and are highly conserved across both prokaryotic and eukaryotic organisms. Genetic mutations that result in loss of RecQ helicase activity gives rise to disorders that are associated with CANCER predisposition and
premature aging.
Relacionados
Inglés
:
Bloom Syndrome
Rothmund-Thomson Syndrome
Werner Syndrome
Nota Histórica
Inglés
:
2007(1990)
Calificadores Permitidos
Inglés
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número del Registro:
52217
Identificador Único:
D053484
Ocurrencia en la BVS
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS