Expresión de búsqueda:
ALPHA-CRYSTALLINS
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DeCS
Descriptor
Inglés
:
alpha-Crystallins
Descriptor
Español
:
alfa-Cristalinas
Descriptor
Portugués
:
alfa-Cristalinas
Sinónimos
Inglés
:
Crystallins, alpha
Categoría:
D12.776.306.366.100
D12.776.580.157
Definición
Inglés
:
A subclass of
crystallins
that provides the majority of refractive power and translucency to the lens (LENS, CRYSTALLINE) in
VERTEBRATES
.
Alpha-crystallins
also act as
molecular chaperones
that bind to denatured
proteins
, keep them in solution and thereby maintain the translucency of the lens. The
proteins
exist as large oligomers that are formed from
ALPHA-CRYSTALLIN A CHAIN
and
ALPHA-CRYSTALLIN B CHAIN
subunits.
Nota Histórica
Inglés
:
2003; for ALPHA-CRYSTALLIN use CRYSTALLINS 1982-2002
Calificadores Permitidos
Inglés
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número del Registro:
37439
Identificador Único:
D038201
Ocurrencia en la BVS
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS