Search on: 15-LIPOXYGENASE 
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Descriptor English:   Arachidonate 15-Lipoxygenase 
Descriptor Spanish:   Araquidonato 15-Lipooxigenasa 
Descriptor Portuguese:   Araquidonato 15-Lipoxigenase 
Synonyms English:   15-Lipoxygenase  
Tree Number:   D08.811.682.690.416.583.500.065
D12.776.556.579.374.568.500.030
Definition English:   An enzyme that catalyzes the oxidation of arachidonic acid to yield 15-hydroperoxyarachidonate (15-HPETE) which is rapidly converted to 15-hydroxy-5,8,11,13-eicosatetraenoate (15-HETE). The 15-hydroperoxides are preferentially formed in NEUTROPHILS and LYMPHOCYTES. 
Entry Combination - descr/qualif English:   Arachidonate 15-Lipoxygenase/antagonists & inhibitors use Lipoxygenase Inhibitors
 
History Note English:   91(87); was see under ARACHIDONATE LIPOXYGENASES 1987-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   19076 
Unique Identifier:   D001093 

Occurrence in VHL:
 

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