Search on: 5,12-DIHETE 
Descriptors Found: 1
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Descriptor English:   Leukotriene B4 
Descriptor Spanish:   Leucotrieno B4 
Descriptor Portuguese:   Leucotrieno B4 
Synonyms English:   LTB4
5,12-diHETE
5,12-HETE  
Tree Number:   D10.251.355.255.100.450.411
D10.251.355.310.166.887.411
D23.469.050.175.450.415
Definition English:   The major metabolite in neutrophil polymorphonuclear leukocytes. It stimulates polymorphonuclear cell function (degranulation, formation of oxygen-centered free radicals, arachidonic acid release, and metabolism). (From Dictionary of Prostaglandins and Related Compounds, 1990) 
Indexing Annotation English:   /biosyn /physiol permitted; DF: note short X ref
History Note English:   94; was LEUKOTRIENES B 1983-93; LEUKOTRIENE B4 was see LEUKOTRIENES B 1983-93 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   31746 
Unique Identifier:   D007975 

Occurrence in VHL:
 

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