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BENSERAZIDE
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DeCS
Descriptor
English
:
Benserazide
Descriptor
Spanish
:
Benserazida
Descriptor
Portuguese
:
Benserazida
Synonyms
English
:
Serazide
Seryltrihydroxybenzylhydrazine
Tree Number:
D02.442.175
Definition
English
:
An inhibitor of
DOPA DECARBOXYLASE
that does not enter the
central nervous system
. It is often given with
LEVODOPA
in the treatment of parkinsonism to prevent the conversion of
levodopa
to
dopamine
in the periphery, thereby increasing the amount that reaches the
central nervous system
and reducing the required dose. It has no antiparkinson actions when given alone.
Pharmacological Action:
Antiparkinson Agents
Dopamine Agents
Enzyme Inhibitors
History Note
English
:
91(79); was see under HYDRAZINES 1979-90; was SERYLTRIHYDROXY BENZYLHYDRAZINE see under HYDRAZINES 1973-78 (Prov 1973-74)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
23953
Unique Identifier:
D001545
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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