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BUPROPION
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DeCS
Descriptor
English
:
Bupropion
Descriptor
Spanish
:
Bupropion
Descriptor
Portuguese
:
Bupropiona
Tree Number:
D02.522.818.110
Definition
English
:
A unicyclic, aminoketone antidepressant. The mechanism of its therapeutic actions is not well understood, but it does appear to block
dopamine
uptake. The hydrochloride is available as an aid to
smoking cessation
treatment.
Indexing Annotation
English
:
do not confuse with Zyban fungicide
Pharmacological Action:
Antidepressive Agents, Second-Generation
Cytochrome P-450 CYP2D6 Inhibitors
Dopamine Uptake Inhibitors
See Related
English
:
Smoking Cessation
History Note
English
:
92; was BUPROPION (NM) 1978-91
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
30220
Unique Identifier:
D016642
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS