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DeCS
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Descriptor English:
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Mechlorethamine
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Descriptor Spanish:
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Mecloretamina
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Descriptor Portuguese:
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Mecloretamina
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Synonyms English:
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Chlorethazine
Chlormethine
Mechlorethamine Oxide
Mustine
Nitrogen Mustard
Nitrogen Mustard N-Oxide
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Tree Number:
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D02.455.526.728.650.529
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Definition English:
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A biologic alkylating agent that exerts its cytotoxic effects by forming DNA ADDUCTS and DNA interstrand crosslinks, thereby inhibiting rapidly proliferating cells. The hydrochloride is an antineoplastic agent used to treat HODGKIN DISEASE and LYMPHOMA. |
Pharmacological Action:
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Alkylating Agents
Antineoplastic Agents, Alkylating
Chemical Warfare Agents
Irritants
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History Note English:
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MECHLORETHAMINE OXIDE was heading 1963-79; NITROGEN MUSTARD N-OXIDE was NITROGEN MUSTARD N-OXIDE (NM) 1984-91
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Allowable Qualifiers English:
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Record Number:
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8635
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Unique Identifier:
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D008466
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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