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CHLORIMIPRAMINE
Descriptors Found:
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DeCS
Descriptor
English
:
Clomipramine
Descriptor
Spanish
:
Clomipramina
Descriptor
Portuguese
:
Clomipramina
Synonyms
English
:
Chlorimipramine
Tree Number:
D03.494.240.194
Definition
English
:
A tricyclic antidepressant
similar
to
IMIPRAMINE
that selectively inhibits the uptake of
serotonin
in the brain. It is readily absorbed from the
gastrointestinal tract
and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
Pharmacological Action:
Antidepressive Agents, Tricyclic
Serotonin Uptake Inhibitors
History Note
English
:
80(75); was CHLORIMIPRAMINE see under DIBENZAZEPINES 1968-79
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
3022
Unique Identifier:
D002997
Occurrence in VHL
:
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