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CHROMOMYCINS
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DeCS
Descriptor
English
:
Chromomycins
Descriptor
Spanish
:
Cromomicinas
Descriptor
Portuguese
:
Cromomicinas
Tree Number:
D09.408.210
Definition
English
:
A complex of several closely related glycosidic
antibiotics
from
Streptomyces griseus
. The major component,
CHROMOMYCIN A3
, is used as a fluorescent stain of DNA where it attaches and inhibits RNA synthesis. It is also used as an antineoplastic agent, especially for solid tumors.
Indexing Annotation
English
:
antineoplastic
antibiotics
Pharmacological Action:
Antibiotics, Antineoplastic
Nucleic Acid Synthesis Inhibitors
History Note
English
:
73(72)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
23195
Unique Identifier:
D002865
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS