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DENOSUMAB
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DeCS
Descriptor
English
:
Denosumab
Descriptor
Spanish
:
Denosumab
Descriptor
Portuguese
:
Denosumab
Tree Number:
D12.776.124.486.485.114.224.060.782
D12.776.124.790.651.114.224.060.782
D12.776.377.715.548.114.224.200.782
Definition
English
:
A humanized monoclonal antibody and an inhibitor of the
RANK LIGAND
, which regulates OSTEOCLAST differentiation and
bone remodeling
. It is used as a
BONE DENSITY
CONSERVATION AGENT in the treatment of
OSTEOPOROSIS.
History Note
English
:
2016 (2004)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
CT
contraindications
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
55976
Unique Identifier:
D000069448
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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