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DIPHENOXYLATE
Descriptors Found:
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DeCS
Descriptor
English
:
Diphenoxylate
Descriptor
Spanish
:
Difenoxilato
Descriptor
Portuguese
:
Difenoxilato
Tree Number:
D03.066.399.300
D03.383.621.349.300
Definition
English
:
A
MEPERIDINE
congener used as an antidiarrheal, usually in combination with
ATROPINE
. At high doses, it acts like
morphine
. Its unesterified metabolite difenoxin has
similar
properties and is used similarly. It has little or no analgesic activity.
Pharmacological Action:
Analgesics, Opioid
Antidiarrheals
History Note
English
:
91(75); was see under ISONIPECOTIC ACIDS 1975-90
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
4212
Unique Identifier:
D004157
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS