Search on: EVEROLIMUS 
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Descriptor English:   Everolimus 
Descriptor Spanish:   Everolimus 
Descriptor Portuguese:   Everolimo 
Tree Number:   D02.540.505.760.500
Definition English:   A derivative of sirolimus and an inhibitor of TOR SERINE-THREONINE KINASES. It is used to prevent GRAFT REJECTION in heart and kidney transplant patients by blocking cell proliferation signals. It is also an ANTINEOPLASTIC AGENT. 
History Note English:   2016 (1997) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   55896 
Unique Identifier:   D000068338 

Occurrence in VHL: 		 

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