Search on:
HEXAMETHONIUM
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
Hexamethonium
Descriptor
Spanish
:
Hexametonio
Descriptor
Portuguese
:
Hexametônio
Tree Number:
D02.092.877.250.592.400
D02.675.276.558.592.500
Definition
English
:
A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the
gastrointestinal tract
and does not cross the
blood-brain barrier
. It has been used for a variety of therapeutic purposes including
hypertension
but, like the other
ganglionic blockers
, it has been replaced by more specific drugs for most purposes, although it is widely used a
research
tool.
Pharmacological Action:
Antihypertensive Agents
Ganglionic Blockers
Nicotinic Antagonists
Entry Combination - descr/qualif
English
:
Hexamethonium
/
analogs & derivatives
use
Hexamethonium Compounds
History Note
English
:
95; was HEXAMETHONIUM (NM) 1980-94
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
32201
Unique Identifier:
D018738
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS