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MERCAPTAMINE
Descriptors Found:
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DeCS
Descriptor
English
:
Cysteamine
Descriptor
Spanish
:
Cisteamina
Descriptor
Portuguese
:
Cisteamina
Synonyms
English
:
Cysteinamine
Mercaptamine
Tree Number:
D02.092.471.562.369
D02.886.489.472.369
Definition
English
:
A mercaptoethylamine compound that is endogenously derived from the
COENZYME A
degradative pathway. The fact that
cysteamine
is readily transported into
LYSOSOMES
where it reacts with
CYSTINE
to form cysteine-cysteamine disulfide and
CYSTEINE
has led to its use in
CYSTINE DEPLETING AGENTS
for the treatment of
CYSTINOSIS.
Indexing Annotation
English
:
do not confuse with
CYSTAMINE
Pharmacological Action:
Cystine Depleting Agents
History Note
English
:
CYSTEINAMINE was see under MERCAPTOETHYLAMINES 1963-66
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
3562
Unique Identifier:
D003543
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS