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MITOMYCINS
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DeCS
Descriptor
English
:
Mitomycins
Descriptor
Spanish
:
Mitomicinas
Descriptor
Portuguese
:
Mitomicinas
Tree Number:
D02.806.400.249
D03.383.097.500
D03.438.473.412.249
Definition
English
:
A group of methylazirinopyrroloindolediones obtained from certain
Streptomyces
strains. They are very toxic
antibiotics
used as
ANTINEOPLASTIC AGENTS
in some solid tumors.
PORFIROMYCIN
and
MITOMYCIN
are the most useful members of the group.
Indexing Annotation
English
:
MITOMYCIN
is also available
Pharmacological Action:
Antibiotics, Antineoplastic
History Note
English
:
82; was MITOMYCIN 1963-81
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
9127
Unique Identifier:
D008937
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS