Search on: MONOCROTALINE 
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Descriptor English:   Monocrotaline 
Descriptor Spanish:   Monocrotalina 
Descriptor Portuguese:   Monocrotalina 
Tree Number:   D03.132.716.500
D03.438.772.500
Definition English:   A pyrrolizidine alkaloid and a toxic plant constituent that poisons livestock and humans through the ingestion of contaminated grains and other foods. The alkaloid causes pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature. Significant attenuation of the cardiopulmonary changes are noted after oral magnesium treatment. 
History Note English:   92; was MONOCROTALINE (NM) 1973-91 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   29959 
Unique Identifier:   D016686 

Occurrence in VHL:
 

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