Search on: PHOSPHOFRUCTOKINASE-1 
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Descriptor English:   Phosphofructokinase-1 
Descriptor Spanish:   Fosfofructoquinasa-1 
Descriptor Portuguese:   Fosfofrutoquinase-1 
Synonyms English:   6-Phosphofructokinase  
Tree Number:   D08.811.913.696.620.225.850.500
Definition English:   An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. D-tagatose- 6-phosphate and sedoheptulose-7-phosphate also are acceptors. UTP, CTP, and ITP also are donors. In human phosphofructokinase-1, three types of subunits have been identified. They are PHOSPHOFRUCTOKINASE-1, MUSCLE TYPE; PHOSPHOFRUCTOKINASE-1, LIVER TYPE; and PHOSPHOFRUCTOKINASE-1, TYPE C; found in platelets, brain, and other tissues. 
Indexing Annotation English:   GEN or unspecified; prefer specifics
See Related English:   Glycogen Storage Disease Type VII
Phosphofructokinase-2
 
History Note English:   2002 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   30875 
Unique Identifier:   D010732 

Occurrence in VHL:
 

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