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QUINACRINE
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DeCS
Descriptor
English
:
Quinacrine
Descriptor
Spanish
:
Quinacrina
Descriptor
Portuguese
:
Quinacrina
Synonyms
English
:
Mepacrine
Tree Number:
D03.494.046.250.760
Definition
English
:
An acridine derivative formerly widely used as an antimalarial but superseded by
chloroquine
in recent years. It has also been used as an anthelmintic and in the treatment of
giardiasis
and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
Pharmacological Action:
Anticestodal Agents
Antimalarials
Antinematodal Agents
Antineoplastic Agents
Enzyme Inhibitors
History Note
English
:
CHINACRIN was see QUINACRINE 1977-93
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
12233
Unique Identifier:
D011796
Occurrence in VHL
:
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DeCS
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