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RANIBIZUMAB
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DeCS
Descriptor
English
:
Ranibizumab
Descriptor
Spanish
:
Ranibizumab
Descriptor
Portuguese
:
Ranibizumab
Tree Number:
D12.776.124.486.485.114.224.060.868
D12.776.124.790.651.114.224.060.868
D12.776.377.715.548.114.224.200.868
Definition
English
:
A recombinant humanized monoclonal antibody fragment that binds VEGF-A to prevent its binding to
VEGFR-1
and
VEGFR-2
receptors. This activity reduces vessel
permeability
and angiogenesis in the treatment of neovascular age-related
MACULAR DEGENERATION.
History Note
English
:
2016 (2005)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
CT
contraindications
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
55979
Unique Identifier:
D000069579
Occurrence in VHL
:
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DeCS
CID-10
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