Search on: SOFOSBUVIR 
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Descriptor English:   Sofosbuvir 
Descriptor Spanish:   Sofosbuvir 
Descriptor Portuguese:   Sofosbuvir 
Tree Number:   D03.383.742.686.850.877.500
D13.695.740.850.877.500
D13.695.827.919.877.500
Definition English:   A uridine monophosphate analog inhibitor of HEPATITIS C VIRUS (HCV) polymerase NS5B that is used as an ANTIVIRAL AGENT in the treatment of CHRONIC HEPATITIS C. 
History Note English:   2016 (2010) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   55930 
Unique Identifier:   D000069474 

Occurrence in VHL:
 

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