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SULBACTAM
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DeCS
Descriptor
English
:
Sulbactam
Descriptor
Spanish
:
Sulbactam
Descriptor
Portuguese
:
Sulbactam
Tree Number:
D02.065.589.099.750.812
D02.886.108.750.812
D03.438.260.825.812
D03.605.084.737.812
D04.075.080.875.099.221.750.812
Definition
English
:
A beta-lactamase inhibitor with very weak antibacterial action. The compound prevents antibiotic destruction of beta-lactam
antibiotics
by inhibiting
beta-lactamases
, thus extending their spectrum activity. Combinations of
sulbactam
with beta-lactam
antibiotics
have been used successfully for the therapy of infections caused by organisms resistant to the antibiotic alone.
Pharmacological Action:
Anti-Bacterial Agents
beta-Lactamase Inhibitors
History Note
English
:
88
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
24415
Unique Identifier:
D013407
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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