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TGF-ALPHA
Descriptors Found:
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DeCS
Descriptor
English
:
Transforming Growth Factor alpha
Descriptor
Spanish
:
Factor de Crecimiento Transformador alfa
Descriptor
Portuguese
:
Fator de Crescimento Transformador alfa
Synonyms
English
:
Epidermal Growth Factor-Related Transforming Growth Factor
TGF-alpha
Tree Number:
D12.644.276.382.750
D12.644.276.963.360
D12.776.467.382.750
D12.776.467.960.360
D23.529.382.750
D23.529.960.360
Definition
English
:
An
EPIDERMAL GROWTH FACTOR
related protein that is found in a variety of
tissues
including
EPITHELIUM
, and maternal
DECIDUA
. It is synthesized as a transmembrane protein which can be cleaved to release a soluble active form which binds to the EGF RECEPTOR.
History Note
English
:
91; was see TRANSFORMING GROWTH FACTORS 1989-90; TGF-ALPHA was see TRANSFORMING GROWTH FACTORS 1989-90
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
29138
Unique Identifier:
D016211
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS