Search on: TETRASPANINS 
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Descriptor English:   Tetraspanins 
Descriptor Spanish:   Tetraspaninas 
Descriptor Portuguese:   Tetraspaninas 
Tree Number:   D12.776.543.982
Definition English:   A large superfamily of cell surface membrane proteins characterized by their four transmembrane domains. They play a role in a variety of processes such as cellular adhesion and motility. They may be involved in the organization of cell surface MEMBRANE MICRODOMAINS that regulate the activation of LEUKOCYTES. 
Indexing Annotation English:   general or unspecified; prefer specifics
See Related English:   MARVEL Domain-Containing Proteins
 
History Note English:   2012 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   54638 
Unique Identifier:   D059470 

Occurrence in VHL:
 

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