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THAPSIGARGIN
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DeCS
Descriptor
English
:
Thapsigargin
Descriptor
Spanish
:
Tapsigargina
Descriptor
Portuguese
:
Tapsigargina
Tree Number:
D02.455.426.392.368.284.500.888
D02.455.849.765.793.888
Definition
English
:
A sesquiterpene lactone found in roots of
THAPSIA
. It inhibits CA(2+)-TRANSPORTING ATPASE mediated uptake of
CALCIUM
into
SARCOPLASMIC RETICULUM.
Pharmacological Action:
Enzyme Inhibitors
History Note
English
:
97; was THAPSIGARGIN (NM) 1979-96
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
32986
Unique Identifier:
D019284
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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