Search on: VENTURICIDINS 
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Descriptor English:   Venturicidins 
Descriptor Spanish:   Venturicidinas 
Descriptor Portuguese:   Venturicidinas 
Tree Number:   D02.540.800
Definition English:   Toxic substances isolated from various strains of Streptomyces. They are 20-membered macrolides that inhibit oxidative phosphorylation and mitochondrial ATPases. Venturicidins A and B are glycosides. Used mainly as tools in the study of mitochondrial function. 
Indexing Annotation English:   uncoupling agents & antifungal antibiotics; from Streptomyces
Pharmacological Action:   Antifungal Agents
Uncoupling Agents
 
History Note English:   91(77); was see under LACTONES 1977-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   15103 
Unique Identifier:   D014698 

Occurrence in VHL: 		 

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