Pesquisa sobre:
CALRETICULIN
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DeCS
Descritor
Inglês
:
Calreticulin
Descritor
Espanhol
:
Calreticulina
Descritor
Português
:
Calreticulina
Categoria:
D12.644.360.381.374
D12.776.157.125.412.374
D12.776.476.387.374
D12.776.503.303
Definição
Inglês
:
A multifunctional protein that is found primarily within membrane-bound
organelles
. In the
ENDOPLASMIC RETICULUM
it binds to specific N-linked
oligosaccharides
found on newly-synthesized
proteins
and functions as a MOLECULAR CHAPERONE that may play a role in
PROTEIN FOLDING
or retention and degradation of misfolded
proteins
. In addition
calreticulin
is a major storage form for
CALCIUM
and functions as a calcium-signaling molecule that can regulate intracellular
calcium
HOMEOSTASIS.
Nota Histórica
Inglês
:
2003; use CALRETICULIN (NM) 1990-2002
Qualificadores Permitidos
Inglês
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número do Registro:
37386
Identificador Único:
D037282
Ocorrência na BVS
:
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CID-10
SciELO
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