Pesquisa sobre: JANUS KINASE 2 
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Descritor Inglês:   Janus Kinase 2 
Descritor Espanhol:   Janus Quinasa 2 
Descritor Português:   Janus Quinase 2 
Categoria:   D08.811.913.696.620.682.725.124.200
D12.776.476.393.200
D12.776.624.664.700.117
Definição Inglês:   A Janus kinase subtype that is involved in signaling from GROWTH HORMONE RECEPTORS; PROLACTIN RECEPTORS; and a variety of CYTOKINE RECEPTORS such as ERYTHROPOIETIN RECEPTORS and INTERLEUKIN RECEPTORS. Dysregulation of Janus kinase 2 due to GENETIC TRANSLOCATIONS have been associated with a variety of MYELOPROLIFERATIVE DISORDERS. 
Nota Histórica Inglês:   2007(1992) 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   52254 
Identificador Único:   D053614 

Ocorrência na BVS: 		 

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