Pesquisa sobre:
NOD2 SIGNALING ADAPTOR PROTEIN
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DeCS
Descritor
Inglês
:
Nod2 Signaling Adaptor Protein
Descritor
Espanhol
:
Proteína Adaptadora de Señalización NOD2
Descritor
Português
:
Proteína Adaptadora de Sinalização NOD2
Sinônimos
Inglês
:
Nucleotide Oligomerization Domain 2 Protein
Categoria:
D12.644.360.024.131.500
D12.644.360.024.307.500
D12.644.360.075.358.500
D12.776.157.057.004.500
D12.776.157.057.068.500
D12.776.476.024.139.500
D12.776.476.024.391.500
D12.776.476.075.358.500
Definição
Inglês
:
A NOD signaling adaptor protein that contains two C-terminal leucine-rich domains which recognize bacterial
PEPTIDOGLYCAN
. It signals via an N-terminal capase recruitment domain that interacts with other
CARD SIGNALING ADAPTOR PROTEINS
such as RIP SERINE-THEONINE KINASES. The protein plays a role in the host defense response by signaling the activation of
CASPASES
and the
MAP KINASE SIGNALING SYSTEM
. Mutations of the gene encoding the
nucleotide oligomerization domain 2 protein
have been associated with increased susceptibility to
CROHN DISEASE.
Nota Histórica
Inglês
:
2007
Qualificadores Permitidos
Inglês
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número do Registro:
52307
Identificador Único:
D053473
Ocorrência na BVS
:
Similar:
DeCS
CID-10
SciELO
LILACS
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