Pesquisa sobre:
PAXILLIN
Descritores Encontrados:
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DeCS
Descritor
Inglês
:
Paxillin
Descritor
Espanhol
:
Paxillin
Descritor
Português
:
Paxilina
Categoria:
D12.644.360.024.309
D12.776.157.057.092
D12.776.476.024.397
D12.776.512.374
D12.776.744.665
Definição
Inglês
:
Paxillin
is a signal transducing adaptor protein that localizes to
FOCAL ADHESIONS
via its four LIM domains. It undergoes
PHOSPHORYLATION
in response to integrin-mediated
CELL ADHESION
, and interacts with a variety of
proteins
including
VINCULIN
; FOCAL ADHESION KINASE; PROTO-ONCOGENE PROTEIN PP60(C-SRC); and PROTO-ONCOGENE PROTEIN C-CRK.
Nota Histórica
Inglês
:
2006(1991)
Qualificadores Permitidos
Inglês
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número do Registro:
50780
Identificador Único:
D051419
Ocorrência na BVS
:
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