1 / 1
|
DeCS
|
|
|
Descriptor English:
|
|
Helix-Turn-Helix Motifs
|
Descriptor Spanish:
|
|
Secuencias Hélice-Giro-Hélice
|
Descriptor Portuguese:
|
|
Sequências Hélice-Volta-Hélice
|
Synonyms English:
|
|
HTH Motifs
|
Tree Number:
|
|
G02.111.570.820.709.600.040.360.360
|
Definition English:
|
|
The first DNA-binding protein motif to be recognized. Helix-turn-helix motifs were originally identified in bacterial proteins but have since been found in hundreds of DNA-BINDING PROTEINS from both eukaryotes and prokaryotes. They are constructed from two alpha helices connected by a short extended chain of amino acids, which constitute the "turn." The two helices are held at a fixed angle, primarily through interactions between the two helices. (From Alberts et al., Molecular Biology of the Cell, 3d ed, p408-9) |
Indexing Annotation English:
|
|
do not confuse with HELIX-LOOP-HELIX MOTIFS
|
History Note English:
|
|
96; was see HELIX-LOOP-HELIX MOTIFS 1994-95
|
Allowable Qualifiers English:
|
|
|
Record Number:
|
|
32734
|
Unique Identifier:
|
|
D019077
|
Occurrence in VHL:
|
|
|
Similar:
|
|
DeCS CID-10 SciELO LILACS LIS
|