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TESTOSTERONE-ESTRADIOL BINDING GLOBULIN
Descriptors Found:
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DeCS
Descriptor
English
:
Sex Hormone-Binding Globulin
Descriptor
Spanish
:
Globulina de Unión a Hormona Sexual
Descriptor
Portuguese
:
Globulina de Ligação a Hormônio Sexual
Synonyms
English
:
Testosterone-Estradiol Binding Globulin
Sex Steroid-Binding Protein
Tree Number:
D12.776.124.790.223.800
D12.776.157.762
D12.776.377.715.182.800
Definition
English
:
A glycoprotein migrating as a beta-globulin. Its
molecular weight
, 52,000 or 95,000-115,000, indicates that it exists as a dimer. The protein binds
testosterone
,
dihydrotestosterone
, and
estradiol
in the
plasma
. Sex hormone-binding protein has the same
amino acid sequence
as
ANDROGEN-BINDING PROTEIN
. They differ by their sites of synthesis and post-translational oligosaccharide modifications.
Indexing Annotation
English
:
does not refer to all sex
hormones
: refers to a specific protein in the blood binding only
testosterone
or
estradiol
; for other sex hormone-binding
globulins
consider
ANDROGEN-BINDING PROTEIN
&
PROGESTERONE-BINDING GLOBULIN
; DF: SHBG
See Related
English
:
Androgen-Binding Protein
History Note
English
:
77; SEX STEROID-BINDING PROTEIN was SEX-STEROID-BINDING PROTEIN (NM) 1981-91; ESTRADIOL-BINDING GLOBULIN & TESTOSTERONE-BINDING GLOBULIN were see SEX HORMONE-BINDING GLOBULIN 1977-92
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
22292
Unique Identifier:
D012738
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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