Search on: LEUKOTRIENES 
Descriptors Found: 1
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Descriptor English:   Leukotrienes 
Descriptor Spanish:   Leucotrienos 
Descriptor Portuguese:   Leucotrienos 
Tree Number:   D10.251.355.255.100.450
D10.251.355.310.166.887
D23.469.050.175.450
Definition English:   A family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway. They participate in host defense reactions and pathophysiological conditions such as immediate hypersensitivity and inflammation. They have potent actions on many essential organs and systems, including the cardiovascular, pulmonary, and central nervous system as well as the gastrointestinal tract and the immune system. 
Indexing Annotation English:   eicosanoids; GEN or unspecified; prefer specifics; /biosyn /physiol permitted
Entry Combination - descr/qualif English:   Leukotrienes/antagonists & inhibitors use Leukotriene Antagonists
 
See Related English:   Receptors, Leukotriene
 
History Note English:   89 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   28158 
Unique Identifier:   D015289 

Occurrence in VHL:
 

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