Expresión de búsqueda:
SEPARASE
Descriptores Encontrados:
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DeCS
Descriptor
Inglés
:
Separase
Descriptor
Español
:
Separasa
Descriptor
Portugués
:
Separase
Categoría:
D08.811.277.656.262.500.792
D08.811.277.656.300.200.792
D12.776.167.552
Definición
Inglés
:
Separase
is a caspase-like
cysteine
protease, which plays a central role in triggering
ANAPHASE
by cleaving the SCC1/RAD21 subunit of the cohesin complex. Cohesin holds the sister
CHROMATIDS
together during
METAPHASE
and its cleavage results in
chromosome segregation.
Nota Histórica
Inglés
:
2014
Calificadores Permitidos
Inglés
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número del Registro:
55268
Identificador Único:
D064247
Ocurrencia en la BVS
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS