Search on: 1,25-DIHYDROXYCHOLECALCIFEROL 
Descriptors Found: 1
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Descriptor English:   Calcitriol 
Descriptor Spanish:   Calcitriol 
Descriptor Portuguese:   Calcitriol 
Synonyms English:   1 alpha,25-Dihydroxycholecalciferol
1 alpha,25-Dihydroxyvitamin D3
1,25-Dihydroxycholecalciferol
1,25-Dihydroxyvitamin D3  
Tree Number:   D04.808.247.222.159.478.387.300
D04.808.247.808.146.478.387.300
D04.808.812.768.196.478.387.300
D10.570.938.146.478.387.300
Definition English:   The physiologically active form of vitamin D. It is formed primarily in the kidney by enzymatic hydroxylation of 25-hydroxycholecalciferol (CALCIFEDIOL). Its production is stimulated by low blood calcium levels and parathyroid hormone. Calcitriol increases intestinal absorption of calcium and phosphorus, and in concert with parathyroid hormone increases bone resorption. 
Indexing Annotation English:   deficiency: coordinate CALCITRIOL /defic (IM) with VITAMIN D DEFICIENCY (IM)
Pharmacological Action:   Bone Density Conservation Agents
Calcium Channel Agonists
Vitamins
 
See Related English:   Receptors, Calcitriol
 
History Note English:   82 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   2151 
Unique Identifier:   D002117 

Occurrence in VHL:
 

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