Search on: 2-MERCAPTOETHANESULFONATE 
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Descriptor English:   Mesna 
Descriptor Spanish:   Mesna 
Descriptor Portuguese:   Mesna 
Synonyms English:   Coenzyme M
2-Mercaptoethanesulfonate  
Tree Number:   D02.455.326.146.100.050.490
D02.886.489.590
D02.886.645.600.055.050.500
Definition English:   A sulfhydryl compound used to prevent urothelial toxicity by inactivating metabolites from ANTINEOPLASTIC AGENTS, such as IFOSFAMIDE or CYCLOPHOSPHAMIDE. 
Pharmacological Action:   Protective Agents
 
History Note English:   92; was 2-MERCAPTOETHANESULFONATE 1977-91 (see under MERCAPTOETHANOL 1977-90); MESNA was see 2-MERCAPTOETHANESULFONATE 1978-91 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   30385 
Unique Identifier:   D015080 

Occurrence in VHL: 		 

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