Search on:
4,5-DIHYDRO-1-(3-(TRIFLUOROMETHYL)PHENYL)-1H-PYRAZOL-3-AMINE
Descriptors Found:
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DeCS
Descriptor
English
:
4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine
Descriptor
Spanish
:
4,5-dihidro-1-(3-(trifluorometil)fenil)-1H-pirazol-3-amina
Descriptor
Portuguese
:
4,5-Di-Hidro-1-(3-(Trifluormetil)Fenil)-1H-Pirazol-3-Amina
Tree Number:
D03.383.129.539.120
Definition
English
:
A dual inhibitor of both cyclooxygenase and
lipoxygenase
pathways. It exerts an anti-inflammatory effect by inhibiting the formation of
prostaglandins
and
leukotrienes
. The drug also enhances pulmonary hypoxic
vasoconstriction
and has a protective effect after
myocardial ischemia.
Pharmacological Action:
Anti-Inflammatory Agents, Non-Steroidal
Cyclooxygenase Inhibitors
Lipoxygenase Inhibitors
History Note
English
:
2005(1991)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
29238
Unique Identifier:
D015772
Occurrence in VHL
:
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DeCS
CID-10
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