Search on: APOPROTEIN(A) 
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Descriptor English:   Apoprotein(a) 
Descriptor Spanish:   Apoproteína(a) 
Descriptor Portuguese:   Apoproteína(a) 
Synonyms English:   Apolipoprotein Lp(a)  
Tree Number:   D10.532.350.500
D12.776.521.400.500
Definition English:   A large and highly glycosylated protein constituent of LIPOPROTEIN (A). It has very little affinity for lipids but forms disulfide-linkage to APOLIPOPROTEIN B-100. Apoprotein(a) has SERINE PROTEINASE activity and can be of varying sizes from 400- to 800-kDa. It is homologous to PLASMINOGEN and is known to modulate THROMBOSIS and FIBRINOLYSIS. 
Indexing Annotation English:   do not confuse with APOLIPOPROTEINS A, normal structural proteins of the alpha-lipoproteins (HIGH DENSITY LIPOPROTEINS)
History Note English:   2007 (1986); use APOLIPOPROTEINS A 1988-2006 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   52270 
Unique Identifier:   D053241 

Occurrence in VHL:
 

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